Novel Food Ingredient

MGCPQQ® is a naturally derived, pure source of pyrroloquinoline quinone disodium salt (PQQ), which is found naturally in trace amounts in plants and meats. MGCPQQ® is a water-soluble, reddish-brown powder harvested using Mitsubishi Gas Chemical’s proprietary fermentation process. The ingredient is registered on the European Union’s list of Novel Food Ingredients.

All-natural MGCPQQ® is manufactured in Japan by Mitsubishi Gas Chemical and is the only PQQ available for purchase by nutraceutical companies and supplement manufacturers in Europe. The natural compound is the world’s first PQQ developed for food application. It’s the same trusted ingredient as BioPQQ®, known in North America and Asia for its safety and effectiveness.

Most Tested. Most Trusted.

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PQQ, created by Mitsubishi Gas Chemical and sold as MGCPQQ® to nutraceutical companies and supplement manufacturers, has been studied in dozens of in-vitro and in-vivo clinical trials. Mitsubishi Gas Chemical’s proprietary fermentation process for harvesting MGCPQQ® naturally is well-controlled and well-documented.

PQQ activates mitochondrial biogenesis, which means it can increase the number of mitochondria in cells. Study results show that PQQ may benefit heart and brain health, and have anti-oxidative, anti-diabetic and neurogenerative effects, (Pyrroloquinoline quinone modulates mitochondrial quantity and function in mice, Stites T., Stomes D., Bauerly K. & Harris C., et al, 2006).

For more information on how the ingredient works and the results of Mitsubishi Gas Chemical’s studies on PQQ, visit the clinical studies page.


Quality, Safety and Standards

MGCPQQ® is a sub-brand to the powerful, safe and effective cognitive health supplement BioPQQ®, which is popular throughout North America. The two consist of the same nutritional ingredient, PQQ. In the U.S. and Japan, BioPQQ is certified safe for intended use via its:

  • NDI (New Dietary Ingredient) notification from the U.S. Food and Drug Administration (FDA)
  • GRAS (Generally Recognized as Safe) status
  • Informed-Choice and Informed-Sport supplement manufacturing certification
  • Certified as a food ingredient by Japan’s MHLW (Ministry of Health, Labour and Welfare)

To learn more about BioPQQ®, visit


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